This 46-year-old patient suffers from Parry-Romberg syndrome. In this case, the syndrome included incomplete facial paralysis on the right and regression of the facial skeleton, especially in the area of the zygomatic arch. This results in a reduced projection of the rightmalar area, a volume deficit in the area of the lower eyelid on the right, a reduced volume of the right upper and lower lip, and a clear asymmetry of the entire face (left and middle picture). She wanted to do without invasive operations such as the correction of the facial skeleton. The patient therefore received a volume augmentation of the right half of her face with multiple autologous fat transfers from the lower abdomen. The right picture shows a clear increase in volume and a harmonization of the facial features due to the improved symmetry after completion of the therapy. The fatty tissue usually heals well and achieves a lasting result.